Drug Standards
Medchemexpress LLC Benzoic acid, 4-[3-(dibutylamino)propoxy]-, hydrochloride (1:1) | 437651-44-0 | 99.3% | C18H30ClNO3 | 500 MG
Dronedarone impurity 25 hydrochloride is identified as an impurity of Dronedarone (HY-75839). It is categorized as a Drug Intermediate, with its pathway listed as "Others."
- Impurity of dronedarone
- Categorized as a drug intermediate
- Molecular formula: C18H30ClNO3
- CAS number: 437651-44-0
- Purity: 99.33%
Apexbio Technology LLC Naftifine HCl 65473-14-5 500mg
Naftifine HCl (CAS 65473-14-5) is a small-molecule inhibitor targeting squalene 2 3-epoxidase It is designed to inhibit this key enzyme thereby disrupting the fungal sterol biosynthetic pathway Naftifine HCl exerts its biological activity primarily through inhibition of squalene 2 3-epoxidase leading to intracellular squalene accumulation and impairment of fungal membrane formation and integrity In in vitro studies Naftifine HCl demonstrates inhibitory activity with IC50 values generally ranging between 20 100 nM against common dermatophytes and fungal pathogens Based on these pharmacological properties Naftifine HCl holds research potential in studies of fungal infections and sterol synthesis inhibition mechanisms including conditions such as tinea pedis tinea corporis and tinea cruris
Medchemexpress LLC Flavopiridol (Alvocidib) | 146426-40-6 | 99.4% | 401.84 | 100 MG
Flavopiridol (Alvocidib) is a broad-spectrum and competitive inhibitor of cyclin-dependent kinases (CDKs), effectively inhibiting CDK1, CDK2, and CDK4. It induces a distinct pattern of ER stress in CLL cells, contributing to cell death through IRE1-mediated activation of ASK1 and potentially downstream caspases. This compound also leads to potent upregulation of several primary response genes (PRGs) with both immediate and long-term effects on their expression. Furthermore, Flavopiridol inhibits cyclin E1 and induces apoptosis.
- Broad-spectrum and competitive inhibitor of CDKs
- Inhibits CDK1, CDK2, and CDK4
- Induces ER stress in CLL cells
- Contributes to cell death via IRE1-mediated activation of ASK1
- Upregulates primary response genes
- Inhibits cyclin E1
- Induces apoptosis
Selleck Chemical LLC Doxazosin
Doxazosin(UK 33274) is a quinazoline-derivative that selectively antagonizes postsynaptic 1-adrenergic receptors
Selleck Chemical LLC Lodoxamide Tromethamine
Lodoxamide Tromethamine (Alomide Lodoxamidetromethamine) is the tromethamide salt form of lodoxamide a synthetic mast cell stabilizing compound with anti-inflammatory activity
Apexbio Technology LLC Fenticonazole Nitrate 73151-29-8 10mg
Fenticonazole Nitrate (CAS 73151-29-8) is a small-molecule inhibitor targeting fungal cytochrome P450 enzyme CYP51A1 (lanosterol 14 -demethylase) It is designed to inhibit the demethylation step required for ergosterol biosynthesis thereby disrupting fungal cell membrane integrity and growth Fenticonazole Nitrate exerts its biological activity primarily through inhibition of CYP51A1 In experimental studies Fenticonazole Nitrate demonstrates inhibitory activity with reported IC50 values for CYP51 inhibition typically in the low micromolar concentration in fungal models such as Malassezia furfur and Candida albicans Based on these pharmacological properties Fenticonazole Nitrate holds research potential in antifungal modes of action studies and antifungal screening assays
Medchemexpress LLC Tenofovir alafenamide hemifumarate | 1392275-56-7 | C21H29N6O5P.1/2 C4H4O4 | 1 ML
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral proagent of Tenofovir. Tenofovir is an HIV-1 nucleotide reverse transcriptase inhibitor.
- Investigational oral proagent
- HIV-1 nucleotide reverse transcriptase inhibitor
- Amidate prodrug with good oral bioavailability
- Increased plasma stability
Selleck Chemical LLC Dexamethasone Acetate 50mg 1177-87-3 NSC 39471
Dexamethasone (NSC 39471) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC Cefpodoxime proxetil S5350-25mg
Cefpodoxime Proxetil is a third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity
Selleck Chemical LLC Tyloxapol S4578-1g
Tyloxapol (Triton WR1339) is a nonionic liquid polymer of the alkyl aryl polyether alcohol type used as a surfactant to aid liquefaction removal of mucopurulent and bronchopulmonary secretions It also blocks plasma lipolytic activity and thus the breakdown of triglyceride-rich lipoproteins Tyloxapol can be used to induce animal models of Hyperlipidemia Atherosclerosis
Sigma Aldrich Fine Chemicals Biosciences Powdered American Ginseng Extract United States Pharmacopeia (USP) Reference Standard | 90045-38-8 | 1.5G
Powdered American Ginseng Extract United States Pharmacopeia (USP) Reference Standard | 90045-38-8 | 1.5G
